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Article
March 10, 1917

THE COLLOIDAL GOLD REACTION OF THE CEREBROSPINAL FLUID IN ACUTE POLIOMYELITIS

Author Affiliations

BALTIMORE

From the Laboratory of Immunology and Bacteriology and the Department of Pediatrics, the Johns Hopkins University, Medical Department.

JAMA. 1917;LXVIII(10):752-754. doi:10.1001/jama.1917.04270030084002
Abstract

The careful work of Peabody, Draper and Dochez,1 in 1912, leaves little to be said, from a diagnostic point of view, concerning the cerebrospinal fluid of patients suffering from acute poliomyelitis. Abramson,2 in 1912, and Neal3 and Klein4 in the recent New York epidemic obtained substantially the same results. Inasmuch, however, as the fluid from such patients has given uniform and significant reactions with Lange's colloidal gold, it has been thought worth while to record the results of the application of this test, as a further contribution to the laboratory knowledge of the spinal fluid in this disease.

The recent small epidemic in Baltimore afforded an opportunity to obtain spinal fluid from a number of patients with poliomyelitis. One of us had the opportunity of doing lumbar punctures on most of the suspects reported to the city health department, as an aid in establishing the diagnosis.

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