Large portions of the lung may be removed from the normal animal with ease and without danger. This is by no means true in case of the sick man afflicted with chronic pulmonary disease. He is generally septic, his resistance is low, his bronchial tree is flooded with a profuse purulent secretion. He is moderately cyanotic. His blood color is low. The diseased lung lobes are firmly adherent to each other and to the diaphragm and the pericardium. The hilum of each lobe is inaccessible. The main lobe bronchus is generally thickened and diseased and unadapted to the technic of closure so successful in animals. The respiratory function and more particularly the circulatory mechanism are distinctly upset by operations for lung resection. The right heart labors in the early postoperative stage to adapt itself to the added demands on the pulmonary circulation. The sound lung labors to accomplish the work
ROBINSON S. THE RESECTION OF LOBES OF THE LUNG. JAMA. 1917;LXIX(5):355–358. doi:10.1001/jama.1917.02590320031007
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