There seems to be great diversity of opinion among operators as to the exact consequences of loss of vitreous humor occurring as a complication in the operation for extraction of cataract. A general idea exists that it is an incident that they would rather not see occur, but that it has but little effect on the result of the operation. It has appeared to me that experience should give us more definite knowledge on this subject, and that we should know with exactness how much it militates against the final result.
Being a more complicated structure than the aqueous, loss of vitreous makes more demands on the reparative powers of the eye than does loss of the aqueous fluid. When once it has escaped, the replaced humor never takes on the histologic make-up of the normal structure. A new fluid secreted from the same source as the aqueous and with
RAY JM. LOSS OF VITREOUS HUMOR IN THE OPERATION FOR EXTRACTION OF CATARACT:ITS IMMEDIATE AND REMOTE EFFECT.. JAMA. 1907;XLIX(1):13–15. doi:10.1001/jama.1907.25320010013002b
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