The most dramatic thyroid problems surround the subject of exophthalmic goiter. The overwhelming character of this malady creates profound impressions on those who observe it, and continually leads to exhaustive studies and paintaking investigations in an effort to master its problems. We may sometimes turn from those who are overwhelmed by excessive toxins to those who live year after year with diminished efficiency and curtailed activities because their thyroids are abnormal. Those who suffer from chronic goiter often need attention as definitely as those who have distinct exophthalmic goiter.
In October, 1915, I reported a study of 137 goiter patients treated by members of the surgical staff of the Roosevelt Hospital. Twenty-five of these patients were classed as showing toxic symptoms in the course of chronic goiter. Since that time I have operated in twelve additional similar cases. This group of thirty-seven cases, selected from a total of 181, represents
DOWD CN. THE CONSTITUTIONAL DISTURBANCES WHICH COME WITH CHRONIC GOITER. JAMA. 1917;LXIX(8):614–619. doi:10.1001/jama.1917.02590350016006
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