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Article
March 31, 1917

REPORT OF VACCINATION EXPERIMENT AT STATE HOSPITAL FOR NERVOUS DISEASES, LITTLE ROCK, ARK.

JAMA. 1917;LXVIII(13):979. doi:10.1001/jama.1917.04270030311017

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Abstract

As there has been some agitation in the state as to the method of vaccination, the following experiment was carried out at the State Hospital for Nervous Diseases, Little Rock, by the courtesy of E. P. Bledsoe, M.D., superintendent:

Twenty-five persons were selected who showed no evidence of previous successful vaccination, and, Nov. 16, 1916, oral vaccination, consisting of one tablet of vaccininum daily for seven days, was administered, this being the time purported to immunize by this method of vaccination. On the eighth day these twenty-five persons, excepting the one who developed smallpox while taking vaccininum, were vaccinated by scarification or the regular method of vaccination, with the following results:

Of the twelve persons vaccinated by Dr. C. A. Arkebauer, by scarification, there were ten positive and two negative; and of the twelve vaccinated by Dr. Pat Murphy, there were ten positive and two negative, and one person developed

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