The factors which enter into the causation of hay fever, or better, hyperesthetic rhinitis, a name proposed by Sajous, are: First, a nervous element; second, a pathologic change in the nasal mucous membrane; third, an exciting constitutional dyscrasia, as a lithemic or uric acid diathesis; and fourth, some adventitious irritation, as dust, pollens or animal emanations.
1. Hyperesthetic rhinitis may occur from an adynamic state of the nervous system irrespective of other causes, or may result from a combination of external irritation and a predisposing neurotic factor. The first class is illustrated by the cases of spontaneous attacks accompanied by sneezing and lachrymation, occurring at any time of day and irrespective of the season. Cases of this character demand a careful investigation as to the cause of nervous trouble, and as treatment, toning up of the general system by baths, exercise, diet, etc., I can not help mentioning a tablet
CURTIS HH. THE ETIOLOGY AND RECENT TREATMENT OF HAY FEVER.. JAMA. 1907;XLIX(2):144–147. doi:10.1001/jama.1907.25320020048001q
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