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May 5, 1917


JAMA. 1917;LXVIII(18):1319. doi:10.1001/jama.1917.04270050021009

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In view of the great frequency with which typhoid vaccination is nowadays performed, and the comparative ease and safety of the procedure, I believe it is wise to bear in mind that untoward results may follow typhoid inoculation, as in the case herewith reported, with the idea, not of paralyzing activities in this direction, but that it is necessary to take proper precautions with patients who are inoculated with typhoid vaccine. I believe that patients who receive the vaccine should be instructed to go home and not to their vocations, where the sudden appearance of certain mental and nervous symptoms would jeopardize their lives.

History.  —W. S., man, aged 24, was one of thirty-three senior students who presented themselves on the morning of Oct. 28, 1916, for the routine typhoid vaccination. He received the same as the other students, 500 million bacilli of the U. S. army strain, nonsensitized, and

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