At the present time, no single method of treatment is adaptable to all cases of malignant disease. Of the many procedures now employed, surgery has the widest adaptation in cases in which the growth is accessible and can be completely eradicated, with the possible exception of superficial epitheliomas in certain localities. In many instances, the lesions must be attacked by a combination of several of the procedures now at our command. Radium and Roentgen rays, while by no means the only agents that may be employed in cases not suitable for operative procedures, have probably the widest field of application next to surgery. When large surfaces must be exposed, as in the treatment of mammary carcinoma with its many harbors of metastasis, and when intensive deep cross-fire radiation is essential, as in the treatment of mediastinal, abdominal or pelvic tumors, Roentgen therapy is the method of choice between the two
PANCOAST HK. MALIGNANT DISEASE OF THE THROAT AND SINUSES: REVIEW OF CASES TREATED BY RADIUM AND ROENTGEN RAYS. JAMA. 1917;LXIX(12):980–982. doi:10.1001/jama.1917.02590390030012
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