In a previous publication, one of us (Walker1) called attention to the prevalence of carriers of Endamocba histolytica among the people of endemic countries, and later (with Sellards2) demonstrated the important rôle which they play in the dissemination of endamebic dysentery. These carriers are always liable to develop dysentery or liver abscess and, because they continue for an indefinite time to pass large numbers of encysted endamebas in their stools, are a constant menace to the community. Consequently the control of this important tropical disease depends primarily on an efficient treatment to eradicate these carriers. Experience has shown that while subcutaneous injections of the soluble salts of emetin are very effective in the treatment of acute dysenteries and liver abscesses of endamebic origin, they fail in many cases to eliminate the encysted endamebas from the intestine. The other drugs which have been employed in endamebiasis, with the possible exception of
WALKER EL, EMRICH W. THE TREATMENT OF CARRIERS OF ENDAMOEBA HISTOLYTICA WITH OIL OF CHENOPODIUM. JAMA. 1917;LXVIII(20):1456–1457. doi:10.1001/jama.1917.04270050158003
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