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June 2, 1917


Author Affiliations

Associate Gynecologist, Providence Hospital; Associate Gynecologist, Casualty Hospital, Washington, D. C. ANACOSTIA, D. C.

JAMA. 1917;LXVIII(22):1601-1604. doi:10.1001/jama.1917.04270060011004

Last year1 I reported 3,952 cases in which pituitary extract had been used. In round numbers there was one maternal death in 565 cases and one fetal death in 146 cases. We shall see what the last year's experience with pituitary extract has brought forth.

I have collected reports on 1,293 additional cases, making a total of 5,245 cases. There are also numerous articles in which the number of cases is not given, Of course, it is realized that statistics here, as in all such subjects, are not to receive too great consideration, but still they certainly do give some idea of the rôle pituitary extract is playing.

One of the most striking points brought out is that the contents of an ampule, 1 c.c., is much too strong to be given in a single dose. It seems to be the consensus of opinion that the dose should be