" Syphilis of innocents " has long since ceased to be the subject of satirical remark, and syphilis itself has long since ceased to be regarded as a purely venereal disease. Syphilis stands to-day as one of the most important diseases affecting the human race, and its study has occupied the thought and activity of observers almost more than that of any other malady, while its literature probably exceeds that relating to any other single disease.
The advances which have been made in the knowledge of the cause, manifestations and results of syphilis during the past fifty years are very great, and have done much to limit its extension by innocent means, and have also served to rob the disease of much of the terror with which it has been surrounded in earlier times. But with all the advances in our knowledge of the disease, and with all our present acquaintance with
BULKLEY LD. SYPHILIS INSONTIUM: A PLEA FOR THE RESTRICTION OF SYPHILIS, AND A SUGGESTION FOR THE PREVENTION OF ITS SPREAD. JAMA. 1893;XXI(20):734–737. doi:10.1001/jama.1893.02420720018004
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