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The very different results obtained by the administration of the thyroid gland, or its extracts, and the reports of its success in so many forms of disease, require some further explanation, and I here give the results of a few observations made during the past six months on its possible physiologic action among the insane.
In the paper read by Dr. C. G. Hill on the subject of thyroid feeding, an analysis of the urine made by Dr. Whitney is given, which shows that though the excretion of chlorids, phosphates, sulphates and to a lesser extent urea are slightly increased, the total solids are decreased, pointing to the non-elimination or non-formation of the more toxic products of metabolism, with the possible exception of the ethereal sulphates. Dr. Haig showed by experimentation on himself that thyroid feeding produced a retention or possibly a reduced production of uric acid. Dr. Perry, in
RICHARDSON H. THE PHYSIOLOGIC ACTION OF THE THYROID GLAND. JAMA. 1897;XXVIII(3):101–102. doi:10.1001/jama.1897.02440030005001c
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