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The treatment of ulcers of the leg has at all times been the crux medicorum and has heretofore, as a rule, been assigned to the field of the surgeon, although in most cases a true affection of the skin. The vast number of remedies advocated for the relief of this pathologic condition only speak for the difficulties offered in its treatment. The entire old arsenal and an array of new remedies, as iodoform, salol, dermatol, europhen, aristol, ichthyol, etc., have been successively brought forth as remedies, par excellence, in the therapeutics of ulcers of the leg. The cause of the failure in the accomplishment of the required result lies not so much in the non-efficaciousness of the above named drugs as in the faulty adaptation to the pathologic condition of the parts. A close study of the relations and the etiologic condition ought to convince us that a particular drug
LOUIS FRANK. THE TREATMENT OF ULCERS OF THE LEG.Read in the Section on Dermatology and Syphilography at the Forty-fourth Annual Meeting of the American Medical Association.. JAMA. 1894;XXII(6):176–179. doi:10.1001/jama.1894.02420850004002a