The hydrochlorate of cocaine, like all new remedies which have promised to mitigate the sufferings of mankind, was hailed with enthusiasm; and in certain lines of practice it is already gaining a firm foothold as a local anæsthetic, principally in ophthalmology and in many operations upon mucous and serous tissues. On the other hand, the subject has lost much of its interest to dental surgeons from the fact that it has proved a disappointment where it was hoped that it would be of the greatest benefit, viz.: as an anæsthetic or obtunder of sensitive dentine. And now that the enthusiasm over the drug has waned, and we begin to investigate its claims with cooler heads and less biased judgment, many of the published accounts of its wonderful effects upon sensitive dentine and the other tissues of the teeth it would seem must have originated very largely in the imagination of
MARSHALL JS. COCAINE IN DENTAL SURGERY. JAMA. 1885;V(11):290–293. doi:10.1001/jama.1885.02391100010001d
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