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October 24, 1885


JAMA. 1885;V(17):471-472. doi:10.1001/jama.1885.02391160023008

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Ptomaines in Cholera-dejecta—Influence of Solar Light on the Bacillus Anthracis and on Vegetation— Prehistoric Skulls at Grenoble—Artificial Fecundation—Two Cases of Hydrophobia.

In a work published last year by M. Gabriel Pouchet, he established the existence of an alkaloidic substance in the dejections of choleraic patients, which was very decomposable and behaved in the manner of a violent poison as regards man and animals. It was interesting to determine, in view of the pathology, the mode of production as well as the rôle of this substance in choleraic manifestations. To enable him to do so, M. Pouchet analyzed broths containing pure cultures of the microbe of Koch, and he was able to establish the presence, though in traces only, of an alkaloid liquid the exterior characters of which (odor, decomposability, toxicity for animals) appeared identical with those of the substance isolated from choleraic dejections. If these results

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