I desire to present for consideration some notes on the use of antipyrin in fevers, because during the past summer I have employed the drug in many cases of fever, and had such good results from it in all cases that I have come to regard it as an eminently useful, safe, and quick antipyretic. Though of recent origin, it has at once assumed a prominent place as an important medicinal agent, and appears destined to take a high rank as an antithermic remedy. It has suddenly and successfully sprung into favor, and as yet has not disappointed those who have used it in a rational manner. I am anxious to learn from the experience of those present whether they have observed served in their cases any unpleasant effects following its use, for as yet I have not seen any of the bad symptoms which have been attributed to it.
ACKER GN. NOTES ON THE USE OF ANTIPYRIN IN FEVERS. JAMA. 1885;V(21):571–572. doi:10.1001/jama.1885.02391200011001c
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