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November 21, 1885


JAMA. 1885;V(21):575-576. doi:10.1001/jama.1885.02391200015003

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We are told by various authors that the heat of fever is due to increased combustion of tissue, or to diminished liberation of heat, or to both together; either of which, theoretically, we might suppose would cause accumulation of heat, and account for the pyrexia. Most recent writers upon the general subject of fever content themselves with a statement of the vital changes that commonly accompany increased bodily temperature, with a mention of the theoretical explanations of the causes of the heat, and an acknowledgement that no satisfactory explanation has yet been devised.

We know that a destruction of tissue out of proportion to the nutritive matter assimilated occurs, and as a consequence heat is produced. While we have, however, more heat evolved from tissue-change in a feverish individual than would be evolved in a healthy person, living upon the same diet, no more tissue-change takes place, and no more

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