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December 19, 1885


JAMA. 1885;V(25):689-690. doi:10.1001/jama.1885.02391240017004

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However conservative the Germans may be in social and political affairs, there is no question as to their being progressive in medical matters. They are eager, restless investigators. Within the last two years synthetical chemistry in Germany has signalized itself by the production of several compounds which have been found to exert marked antipyretic power. Their names have already become familiar to the medical profession throughout the civilized world. Antipyrin, was derived from chinoline by L. Knorr, a chemist of Erlangen, and brought to the notice of the profession in 1884, by Dr. Filehne through the columns of the Zeitschrift für klinische Medicin. Kairin also was introduced into use in medicine by Filehne, while thallin was discovered by Skraup, and recommended as a febrifuge by Dr. yon Jaksch, of Vienna. The rapidity with which their employment has spread among the clinicians of Europe and in this country is astonishing, and

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