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September 18, 1915


JAMA. 1915;LXV(12):1029. doi:10.1001/jama.1915.25810120003015d

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In bacteriologic work, the time element is a matter of considerable importance, both for purposes of rapid and accurate diagnosis and in the rapid preparation of autogenous vaccines. In the treatment of many acute infections, especially in sepsis following operation, childbirth or wound infection, it is often very desirable to have an autogenous vaccine prepared over night, when possible. A satisfactory culture is often delayed by the breakage of the old style loop, made with the glass rod and platinum wire. The rod breaks, when carried in the case, and even when flamed, the glass breaks easily, when too quickly heated. The loop may be lost in the midst of an attempt at obtaining flakes from a fluid medium, and the whole process of culture made difficult or even impossible by the loss of the loop when it is most needed. A new unbreakable loop is the thing sought, and

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