Why an impregnated ovum should implant and develop outside the uterus so relatively frequently in the human species and fail to do so in lower animals is a question the answer to which has been sought through investigation by clinicians and laboratory workers for a great many years. Clinicians agree that ectopic gestation is a frequent abnormality of early pregnancy but vary in their estimates of frequency depending on whether their clinical experience has been gained as a necropsy surgeon, a gynecologist, an obstetrician or a general practitioner. The large number of case reports indicate the frequency with which this condition is met by surgeons, but is too irrelevant to be of aid in discussing the subject statistically. In this paper, a statistical study of a definite number of patients will be made in order to estimate the relative frequency of ectopic gestation to disease in general, to women's disease,
SPALDING AB. RELATIVE FREQUENCY OF ECTOPIC GESTATION. JAMA. 1915;LXV(14):1156–1158. doi:10.1001/jama.1915.02580140006002
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