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Article
June 3, 1911

VANADIUMISM

Author Affiliations

CARNEGIE, PA.

JAMA. 1911;LVI(22):1648. doi:10.1001/jama.1911.02560220024010

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Abstract

Vanadium is a metal named by Sefström, in 1830, in honor of the northern goddess Vanadis (the German Freya). The metal is of no importance technically, although various forms of it are valuable. The pentoxid is used in photography as a developer. Vanadium chlorid and trioxid are used as mordant in printing fabrics; the trioxid is used also in the manufacture of steel, in making easily malleable and ductile alloys. Vanadium pentoxid has been used in diseases due to defective metabolism; there is not, however, enough clinical evidence to justify its use as a medicine.

Vanadiumism is a chronic intoxication caused by ingestion or absorption of some forms of vanadium, either industrially, medicinally, or accidentally. The principal lesions are found in the lungs, kidneys, and gastro-intestinal tract. The lungs are highly congested and show a marked destruction of alveolar epithelium. The kidneys reveal congestion due to continuous irritation and, at

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