American investigations concerning blastomycosis in man, and closely related or identical processes, have reached considerable proportions. This work begins with Gilchrist's description of his first case of blastomycetic dermatitis. Almost two score of similar cases have since been reported and the mycology often clearly set forth. The next important step consisted of the work of Rixford and Gilchrist on the so-called protozoic disease, their results showing the identity of the minute anatomy of the skin lesions in this disease and in blastomycetic dermatitis. However, it seems that Rixford and Gilchrist were in error in concluding that the micro-organism in the protozoic disease is a protozoon, for Ophüls and Moffit1 demonstrated in a thorough manner that the organism is a mold-fungus. Another important feature is that the fungus of Ophüls and Moffitt, as nearly as one can tell from a published description, is identical with the Oidium hyphomycoide isolated by
THE IDENTITY OF SYSTEMIC BLASTOMYCOSIS AND THE SO-CALLED PROTOZOIC DISEASE.. JAMA. 1903;XL(21):1444. doi:10.1001/jama.1903.02490210036008
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