With the increasing number of tests for the presence of sugar in the urine has come an attempt at greater delicacy in the reaction involved. Just as Fehling's test far exceeded in sensitiveness some of the older methods for the detection of sugar, so the newer tests recommended from time to time have as a rule been characterized by the property of revealing smaller and smaller amounts of the carbohydrate. With the exception of the fermentation test, most of the reactions are really indirect in indicating the presence of sugar. Most of them are reduction tests involving the use of salts of copper or other metals.
Inasmuch as other urinary components besides sugar may reduce the cupric solutions, it is sometimes difficult to decide whether traces of observed reaction are due to sugar or to other constituents such as creatinin. From this point of view a reagent may sometimes be
SUGAR IN NORMAL URINE. JAMA. 1915;LXV(20):1732. doi:10.1001/jama.1915.02580200046016
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