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November 27, 1915

THE ACTION OF RADIUM ON CANCERS OF THE PELVIC ORGANS: A CLINICAL AND HISTOLOGIC STUDY

JAMA. 1915;LXV(22):1879-1886. doi:10.1001/jama.1915.02580220019008
Abstract

Since April, 1914, I have treated 112 cases of malignant growths of various regions of the body with radium. Forty-eight of these occurred in pelvic organs. Forty-one of these pelvic cancers are considered in this paper. Thirty-six were in the uterus, five in the rectum and three in the bladder. The tumors were inoperable, recurrent or operable carcinomas. Twenty-four were inoperable, nine recurrent and eight operable.

Ten of the inoperable and three of the recurrent carcinomas were thoroughly cauterized or excochleated and then cauterized preceding the application of radium. Broken-down tissue and débris were thereby as completely removed as possible, and the extent of the intensity of the gamma rays into the depths of the tissues correspondingly increased. The operable cases were subjected to an extensive vaginal cauterization and an abdominal panhysterectomy. As soon as the patient recovered from the operation, radium was inserted into the crater of the broad

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