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November 27, 1915

On Pharmaco-Therapy and Preventive Inoculation Applied to Pneumonia in the African Native. With a Discourse on the Logical Methods Which Ought to be Employed in the Evaluation of Therapeutic Agents.

JAMA. 1915;LXV(22):1938. doi:10.1001/jama.1915.02580220078038

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This book consists of a report to the Witwatersrand Native Labor Association on work undertaken under its auspices directed to the discovery of some method of mitigating the ravages of pneumonia among the native laborers in the Rand mines in South Africa. The material was published in the London Lancet in 1912 and 1914. The outstanding result of this investigation appears to be that the prevalence of pneumonia among the native workers in the Rand mines is to be ascribed to the bringing together in close contact in compounds of a population which has, as a racial character, a low resisting power to the pneumococcus, and that it is possible by means of prophylactic injection of pneumococci to increase greatly the resistance to pneumococcus infection and thus diminish the incidence and death rate from pneumonia among the native laborers. When the author says that in taking up experimental work on

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