Although Cottle1 described a case of what we now believe to have been angiokeratoma as early as 1877, and Crocker,2 Colcott Fox3 and Dubreuilh4 reported examples of the disease as instances of unusual varieties of verruca a few years later, it was not until the publication of Mibelli's5 classical description, in September, 1889, that a careful and accurate delineation of the clinical and pathologic features of the malady was available. Mibelli's case was in a young girl, and the disease, which had been present for about five years, involved the dorsal surfaces of the fingers and toes.
The lesions varied in size from that of a hemp-seed to that of the head of a large pin, and were distributed along the course of the superficial capillaries, which were slightly dilated and more prominent than usual. The patient had for several years suffered from recurring attacks
SUTTON RL. A CLINICAL AND HISTOPATHOLOGIC STUDY OF ANGIOKERATOMA OF THE SCROTUM. JAMA. 1911;LVII(3):189–192. doi:10.1001/jama.1911.04260070193003
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