At the eighth annual meeting of this society, May, 1907, there was presented a paper embodying the results of certain investigations by Holmes C. Jackson and myself entitled, "The Physiologic Action, Elimination and Therapeutic Application of Sodium Cacodylate, Used Hypodermatically."1
Inasmuch as certain authorities have so emphatically insisted that sodium cacodylate is possessed of no arsenical properties, either physiologic or therapeutic,2 it may not be amiss for me to summarize our findings as to that particular point and, at the same time, to state that other observers, notably Runnels,3 have confirmed many of our statements.
Our experiments were conducted with great care at Bender Hygienic Laboratory in Albany, N. Y., and were made not only on dogs and rabbits, but on human beings. We found that the body possesses the power of decomposing the organic compound into an active inorganic form when injected intramuscularly; that it is
DAWES SL. THE THERAPEUTIC VALUE OF SODIUM CACODYLATE. JAMA. 1911;LVII(6):480–482. doi:10.1001/jama.1911.04260080044014
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