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August 12, 1911


Author Affiliations

Junior Staff Physician, Cincinnati Hospital: Instructor in Medicine, University of Cincinnati CINCINNATI

JAMA. 1911;LVII(7):562-563. doi:10.1001/jama.1911.04260080126012

In spite of the progress made in the knowledge of the physiology of the pancreas, its diseases remain difficult and uncertain of diagnosis. The cause of this is apparent in that the clinical aspects of pancreatic disease are in most instances indefinite and not characteristic, and many of the laboratory aids have not proved efficient. My desire to test the value of the newer methods devised for diagnosis prompted some work along this line in the Klinik von Noorden, in which I was associated in the work with Docent Dr. Salmon.

The newer methods of determining the pancreas function for diagnostic purposes aim to test for the presence of the ferments in the stool. To facilitate rapid peristalsis after a breakfast of mixed food followed by an enema, calomel 0.2 gm. and phenolphthalein 0.5(as recommended by Muller) prove very satisfactory.

The two ferments made use of in the determination from