The common expression that "Man is as old as his blood-vessels" is no longer tenable. We now know that his growth and his manifest age depend more on the glands of the body which control function and metabolism, as well as the vessels themselves.
Inasmuch as the importance of the duct and the ductless glands is now known to us, we see why there should be, proportionately, so few anomalies among them in comparison with those in less important structures of the body.
It is becoming more and more apparent that of the various ductless glands the thyroid is one of the most important in its control of the body metabolism, as well as in the maintenance and stimulation of function in many of the associated glands. While various diseases or changes in its structure are fairly common, marked anomalies are exceedingly rare.
The first consideration in the study of
MAYO CH. LINGUAL, SUBLINGUAL AND OTHER FORMS OF ABERRANT THYROIDS. JAMA. 1911;LVII(10):784–786. doi:10.1001/jama.1911.04260090006003
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