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July 18, 1903


JAMA. 1903;XLI(3):192. doi:10.1001/jama.1903.04500010048023

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Ogden, Utah, July 7, 1903.

To the Editor:—Will you kindly inform me through The Journal, the nature and results of Porta's experiments on ligation of the aorta? I find references to them in several works, but none of them give any details. H. B. F.

Ans.—One of the gems in medical reference libraries is a handsome folio published in Italian at Milan in 1845 by L. Porta,* professor of surgery at Pavia. It contains 439 pages with a number of plates. In it he reports 600 experiments on 270 animals, including rabbits, dogs, sheep, goats, horses, asses and beeves, but principally on dogs, as he considered their physical organization as resembling most closely that of man. He reports the details of 113 experiments, undertaken to determine what becomes of a ligature left on an artery, and what changes are induced in the artery and in the circulation by ligature,

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