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Article
November 11, 1911

VARIATIONS IN THE PHAGOCYTIC AND OTHER POWERS OF LEUKOCYTES

Author Affiliations

CHICAGO

From the Memorial Institute for Infectious Diseases.

JAMA. 1911;LVII(20):1579-1583. doi:10.1001/jama.1911.04260110079001
Abstract

In the course of the recent study of phagocytosis, inaugurated by the discovery of opsonic substances in the blood and other fluids, it has been observed by various investigators that, contrary to the original belief of Wright and others, the phagocytic power or activity of the leukocytes is subject to considerable variation independently of variations in the opsonic content of the blood. It is the purpose of this article to review briefly the observations touching variations in the phagocytic and allied powers of leukocytes under different conditions, because it seems to me that the results at hand have a direct bearing on the larger problem of the anti-infectious powers of the blood as a whole.

The phagocytic power of leukocytes from a particular source may be compared with that of other leukocytes by finding the amount of phagocytosis performed by each under strictly comparable conditions. For such purpose the phagocytic

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