There are no more interesting and few more mysterious quesions in the field of physiologic research than those concerned with the problem of fat metabolism. As a pathologic process, an abnormal fatty condition has been discovered in various organs; one of us (Guthrie) reported a case of necrosis (with fatty change) of the kidney, in the Section on Surgery of this Association at its New Orleans meeting. Reported cases of abnormal adipose conditions of the mammary glands are rare.
Cases of unusual non-neoplastic enlargement of the mammary glands have been reported from time to time as examples of diffuse idiopathic hypertrophy of these structures. One of us (Albert1), in reporting a case of this kind a year ago, also reviewed the descriptions of the sixty-nine other cases which had been previously reported. Clinically, cases of idiopathic hypertrophy may be divided into (1), those associated with gestation and (2), those
GUTHRIE JR, ALBERT H. ADIPOSITY OF THE MAMMARY GLANDS. JAMA. 1911;LVII(20):1583–1585. doi:10.1001/jama.1911.04260110083002
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