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Article
November 11, 1911

THE INFECTIVITY OF THE SECRETIONS AND THE DESQUAMATING SCALES OF MEASLES

Author Affiliations

Passed Assistant Surgeon, U. S. P. H. and M.-H. S. WASHINGTON, D. C.

From the Hyglenic Laboratory U. S. Public Health and Marine-Hospital Service.

JAMA. 1911;LVII(20):1612-1613. doi:10.1001/jama.1911.04260110112015
Abstract

I.—SECRETIONS  In a previous communication1 we reported two experiments with nasal and buccal secretions from cases of measles. In the first experiment we inoculated three monkeys with secretions obtained from a patient about twenty-four hours after the first appearance of the eruption. None of these animals gave any recognizable evidence of a reaction. In the second experiment we inoculated monkeys serially with secretions obtained from a patient on each of three successive days, beginning with the appearance of the eruption. The results of these serial inoculations, checked by passage experiments, clearly demonstrated that the mixed buccal and nasal secretions in this case were certainly infective at the time of the beginning rash and again forty-eight hours later. After the publication of these results an opportunity to carry our experiments further and, if possible, to determine the duration of infectivity of the secretions, presenting itself, we made inoculations from five additional

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