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While I have no idea of advocating the removal of the appendix as a cure for pernicious vomiting of pregnancy, I take this opportunity of calling attention to the fact that an inflamed appendix may at times be a form of peripheral irritation sufficient to cause hyperemesis.
—The patient, a primipara, aged 20, gave the following history when she first came under my observation: There had never been any marked irregularity in menstruation, although she. was hysterical and had somewhat marked exacerbations at the periods. For two years previous to my first visit there had been occasional attacks of cramps, with pain in the region of the appendix, attended with vomiting and fever. A diagnosis of appendicitis had already been made by other physicians and operation had been advised. When I saw the patient she was about four months pregnant and had had repeated attacks since conception had taken
RODGERS MA. A CASE OF APPENDICITIS, ASSOCIATED WITH HYPEREMESIS GRAVIDARUM.. JAMA. 1907;XLIX(24):2006. doi:10.1001/jama.1907.25320240042003b
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