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Cincinnati, Nov. 30, 1907.
To the Editor:
—Dr. Walter B. Chase, in his excellent article on "Buried Sutures and Ligatures," in The Journal, Nov. 30, 1907, says very correctly that "it is important to remember in this connection that catgut can be so over-chromicized as to render it unabsorbable and make it as objectionable as silkworm gut." This is all very true, but it does not go far enough. My experience has been to the effect that the heavy and hard catgut, chromicized to last twenty days, is very liable to last forever unless it is removed. It has not, in my experience, been the cause of any infection whatever, but it has repeatedly been the cause of a chemical disintegration of the tissues resulting in the formation of a sinus and the seemingly interminable discharge of chromicized and consequently entirely sterile serum. When this exosmotic current is once established
Reed CAL. Twenty-Day Catgut.. JAMA. 1907;XLIX(24):2020. doi:10.1001/jama.1907.02530240056014
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