The frequency with which Peruvian balsam is employed both as a surgical dressing and in ointments for the local treatment of skin diseases without a thought regarding its possible toxicity leads me to report the following case:
—George S., aged 7, had always been a robust, healthy boy of normal development. Had measles several years ago, but had had no acute illness within the past year. In March, 1906, developed scabies, and when presented for treatment the eruption was scattered over the entire body. Sulphur ointment (10 per cent.) did not control the spread of the parasite and an ointment with 10 per cent. Peruvian balsam was employed twice daily. It was applied over the entire body-surface. Under this treatment the eruption disappeared in five weeks. In May of the same year I was called to see the child and found his abdomen distended with ascites, his face, arms,
HOFFMAN LH. NEPHRITIS FOLLOWING EXTERNAL APPLICATIONS OF BALSAM OF PERU.. JAMA. 1907;XLIX(25):2086. doi:10.1001/jama.1907.25320250038002c
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