Phlyctenular conjunctivitis and keratitis (conjunctivitis eczematosis, phlyctenulosis) constitute one of the most frequent ocular maladies of childhood. The dominant characteristics of the disease are, first, its chronicity and, second, its tendency to recurrences. Usually it is not reckoned as a serious ocular malady, either in its clinical course or in its sequelæ. An extended experience, however, and a careful analysis of the clinical course and sequelæ of phlyctenular trouble neither justify this assumption nor satisfy the conscientious scientist with the results obtained by present methods of treatment. When there is taken into account the suffering experienced by many such patients, the prolonged invalidism they must undergo, the unheralded acute attacks of frequent occurrence which they must accept, the inroads on their visual acuity to which each new attack subjects them, the anxieties of parents as to the outcome of the attacks, the educational loss incident to the patient being compelled
TIVNEN RJ. TUBERCULIN AS A DIAGNOSTIC AND THERAPEUTIC AGENT IN THE TREATMENT OF CONJUNCTIVITIS ECZEMATOSA (PHLYCTENULAR CONJUNCTIVITIS AND KERATITIS): BASED ON THE STUDY OF FIFTY OASES. JAMA. 1911;LVII(24):1886–1891. doi:10.1001/jama.1911.04260120076003
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