It is not without considerable diffidence that I present a paper on this subject, about which so much has been written, so many different opinions have been expressed as to its etiology, and as many sure cures have been presented, but which still has remained the same old pruritus to plague our patients and baffle our skill. I believe the correct etiology has not yet been published, and cures have mostly been temporary improvement.
As a preliminary statement and in connection with this work, it must be understood that I have reference only to the true pruritus ani that has the constant symptoms of thickened skin, radiating in folds; macerated in most cases, and with lack of pigmentation, skin fissures and a parchment-like condition of the skin. Scratching or rubbing the parts gives no relief. Itching occurs with great regularity, particularly when the patient prepares for bed and in the
MURRAY DH. PRURITUS ANI: THE PROBABLE CAUSE AND AN OUTLINE OF TREATMENT: A PRELIMINARY REPORT, BASED ON RESULTS OF ORIGINAL RESEARCH. JAMA. 1911;LVII(24):1913–1914. doi:10.1001/jama.1911.04260120103010
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