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December 16, 1911

CULTURES FROM THE THYROID GLAND IN GOITER: A BACTERIOLOGIC -STUDY OF FOURTEEN CASES

Author Affiliations

PHILADELPHIA

From the Laboratory of Clinical Pathology, Philadelphia Polyclinic and College for Graduates in Medicine.

JAMA. 1911;LVII(25):1988. doi:10.1001/jama.1911.04260120178014
Abstract

The frequent occurrence of hyperthyroidism in certain districts of both Europe and this country, the acute exacerbations that occur in the course of this disease and the occurrence of the disease in several members of the same family are facts of especial interest. Therefore, the study of these cases was undertaken to determine, if possible, whether infection played a rôle in the etiology of hyperthyroidism.

The cultures from these patients, with the exception of that from the first, who was a private patient under my care, were obtained from some of Dr. John B. Deaver's patients at the time of operation at the German Hospital. The primary cultures were made in bouillon and on blood-serum and further carried out on agar, glucose agar, potato, gelatin, litmus-milk, etc. For anaerobic organisms, cultures were made on agar.

The cultures were made according to the method of obtaining cultures from tissues at autopsy—by

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