As is the case in so many other infections, especially those manifesting themselves as more or less chronic processes, the natural tendency in amebic infections of the colon is toward recovery.
In routine post-mortem examinations in Manila, all stages of healing and even healed amebic ulcers are very frequently encountered where amebic disease had not been suspected during life, and where no dysenteric therapeutics had been employed. Furthermore, we have a large number of records of cases of undoubted amebic ulceration of the colon, characterized by an unmistakable clinical picture with amebas in the stools and in some cases the diagnosis confirmed by sigmoidoscopic examination, in which apparent recovery took place without any special or sufficient treatment and in which postmortem examination from one to five years later failed to show any ulceration, visible scarring or other abnormality of the colon.
We conclude from these facts not only that there
MUSGRAVE WE. THE TREATMENT OF INTESTINAL AMEBIASIS. JAMA. 1912;LVIII(1):13–18. doi:10.1001/jama.1912.04260010015005
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