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—Miss P., a young woman aged 27, with good family history, presented herself suffering from recurring erythema multiforme which had afflicted her since childhood. It reappeared every year, reaching its greatest intensity during August and September, and then almost disappeared during the winter. The disease started with papules scattered over various portions of the body, being worse on the arms and legs, next on the buttocks, and lastly on the trunk. These papules would rapidly form vesicles and bullæ, then, breaking down, would coalesce in large patches, leaving a moist, ulcerated surface, which would finally dry up, leaving a brown stain. This process was accompanied by a most intense itching and burning, disturbing the sleep and impairing the general health.
Treatment and Course.
—When I first saw her, Aug. 5, 1911, she had a small papular eruption on the arms, principally, with a few scattered spots over the body
CUTHBERTSON W. CACODYLATE OF SODA IN THE TREATMENT OF RECURRING ERYTHEMA MULTIFORME (ERYTHEMA PERSTANS): REPORT OF A CASE. JAMA. 1912;LVIII(1):30–31. doi:10.1001/jama.1912.04260010032009
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