In June, 1910, the late Dr. N. P. Dandridge proposed the systematic handling of all wounds, punctured, penetrating or lacerated, with the aim of ascertaining the best methods of treating such cases at a large general hospital, particularly with reference to tetanus prophylaxis. As is well known, to avoid the development of tetanus we must begin by treating, in a thorough surgical manner, the wound received. The use of antitetanic serum as a prophylactic agent was resorted to in a large series of cases, in order to test its value.
The following list of instructions were placed in each surgical ward:
The interns will pleasecarry out the instructions mentioned below for the following classes of cases.
1. All perforating, penetrating or lacerating wounds contaminated directly by soil or manure, especially those contracted in the streets or about stables.
2. All blank-cartridge and giant-cracker perforating and lacerating wounds.
BERGHAUSEN O, HOWARD CE. THE TREATMENT OF WOUNDS, WITH REFERENCE TO TETANUS PROPHYLAXIS. JAMA. 1912;LVIII(2):104–105. doi:10.1001/jama.1912.04260010106013
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