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Perhaps there is no province of medicine that has elicited such sustained interest as that devoted to circulatory diseases. Every year sees the appearance in text-books, systems of medicine and current journals of an increasing number of articles on the heart, some of them voluminous in character, some inclusive and some devoted to limited fields.
Comparative anatomy, physiology and the clinic have been peculiarly busied with the subject in the last few years, so that it would hardly be an exaggeration to say that even in the last lustrum almost a complete revolution has been wrought in our ideas of the physiology and pathology of the heart.
More especially has the investigation of these later years taught us that, though the heart in the totality of its structure and the totality of its function operates to forward the circulation, the totality of structure is the combination of distinct anatomic units
MEARA FS. TREATMENT OF ACUTE ENDOCARDITIS AND MYOCARDITIS. JAMA. 1912;LVIII(5):317–322. doi:10.1001/jama.1912.04260020001001
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