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February 17, 1912

EXPERIENCES WITH SALT RESTRICTION IN NEPH RITIC EDEMA

JAMA. 1912;LVIII(7):462-465. doi:10.1001/jama.1912.04260020146003
Abstract

SALT EQUILIBRIUM  The sodium chlorid in the body fluids is normally maintained at a constant level. Below and above this level normal function becomes perverted. Hence the body tenaciously retains a definite percentage of sodium chlorid and reacts by an exaggerated elimination when its intake is increased, by a depression and finally a complete cessation of its output when the intake is decreased. So long as the means of output remain competent salt accumulation is merely temporary. About 2 gm. of sodium chlorid per diem suffice to maintain salt equilibrium and this amount at least must daily be added to the diet. Sodium chlorid in this respect occupies a peculiar position in our dietary, inasmuch as it is the only minera constituent of the food that must be artificially supplied.1

SALT ELIMINATION  The elimination of sodium chlorid is chiefly a function of the kidneys. Some sodium chlorid is eliminated

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