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Article
February 17, 1912

THE JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

JAMA. 1912;LVIII(7):482-486. doi:10.1001/jama.1912.04260020166019
Abstract

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SATURDAY, FEBRUARY 17, 1912 

THE OPHTHALMIC REACTION AS A DIAGNOSTIC TEST FOR TYPHOID  Recently Austrian has described1 an ophthalmic reaction in typhoid which may prove a valuable diagnostic aid. The reaction is similar in principle to Calmette's ophthalmic reaction in tuberculosis, and was first described in 1907 by Chantemesse,2 who obtained positive results in each of seventy cases of typhoid and negative results in forty-nine of fifty control cases. Floyd and Barker,3 using a modification of the same technic, obtained positive reactions in 96 per cent, of typhoid cases and negative results in 84 per cent, of controls. Other investigators have obtained a variety of results in both typhoid and control cases, and some have concluded that the reaction is not

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