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July 22, 1905

The Dangers of Acetanilid.

JAMA. 1905;XLV(4):252. doi:10.1001/jama.1905.02510040024010

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Dodge City, Kan., July 14, 1905.

To the Editor:  -I was walking along the street some months ago and overtook my venerable friend, the Methodist minister, who said "Doctor, I'm glad to see you. What is antikamnia?" I told him that it is a mixture of uncertain composition, used with greater or less success for the relief of pain; that its principal constituent is acetanilid, a valuable remedy under certain conditions, but dangerous when used by the laity.The old gentleman took from his vest pocket a little square box containing twenty-five tablets of about five grains each. The box was labeled "antikamnia," and the legend declared that the remedy would cure a number of unpleasant and more or less dangerous conditions to which humanity is subject, but there was not a word to indicate the size of the dose or the frequency with which it might be repeated. The

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