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In using cocain as a preliminary to cauterization of chancroids I have arrived at the conclusion that the drug is useful aside from its anesthetic properties. By the application of a tablet containing one-fourth to one-half grain of the drug the ulcer within a few minutes is transformed into a vascular, healthy surface from which exudes a bloody serum. The soluble tablet is applied with a small cotton swab, moistened to facilitate the dissolving of the tablet. The drug is "rubbed" into the ulcer lightly with the swab. The application of cocain in this manner once or twice daily is of great service, especially when the sore is inclined to be sluggish. Its use is of necessity restricted to small areas, but is not confined to chancroid. The drug acts in effect by inducing hyperemia. The change in the appearance of the ulcer is really marvelous. The action of the
Lydston GF. COCAIN IN CHANCROID AND SLUGGISH ULCERS. JAMA. 1912;LVIII(8):551. doi:10.1001/jama.1912.04260020235013
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