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January 5, 1895


JAMA. 1895;XXIV(1):25-26. doi:10.1001/jama.1895.02430010043003

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The medical world has heard but little of the bacillus of bilious fever. The éclat which attended the recognition of the spirillum of cholera and the bacillus of tuberculosis was not extended to the recent announcement of Dr. Domingos Friere, of a bacillus similar to that of Tommassi-Crudeli in the bilious fevers of hot climates. Yet locally, in the place of its origin, this announcement created such a disturbance in the medical atmosphere as to agitate not only the professional but the daily press; and this because in addition to the intrinsic importance of the alleged discovery, the question was incidentally raised of the value of Freire's inoculations with attenuated cultures in immunizing against yellow fever. Many letters were published, copies of which are now before us, from which we outline in a suggestive way the manner in which the announcement was received in Rio de Janeiro. It appears from

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