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January 5, 1895

The Practical Importance of Well Established Facts in Therapeutics.

JAMA. 1895;XXIV(1):30. doi:10.1001/jama.1895.02430010048012

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To the Editor:  —Dr.N.S.Davis puts the questions: If alcohol when taken into the living body directly diminishes nerve sensibility, muscular force, and so alters the constituents of the blood as to retard both the internal distribution of oxygen and natural tissue metabolism in direct proportion to the quantity to be taken (the established fact according to Dr. Davis), why do we continue to speak and write concerning it, or to use it, as a stimulant, heart tonic or restorative agent? The answer seems to be that experience proves that we are right in spite of the supposed established facts.Let me briefly illustrate: In the year 1870 I started to walk from Courmayeur to Chamounix via the Col du Géant, a climb of 10,000 feet and a march of some six or seven hours over the Mer de Glace. I arrived at the summit of Col between 9 and 10

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