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March 30, 1912

Serum Diagnosis of Syphilis and the Butyric Acid Test for Syphilis.

JAMA. 1912;LVIII(13):961. doi:10.1001/jama.1912.04260030359040

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This edition of Noguchi's book is a restatement of the method and results which he published in the first edition. It is valuable as giving his latest views on the subject, but contains no very important additions. The chief addition is a study of the effect of treatment on the serum-test of syphilis, which is interesting especially because of the use of a quantitative estimation of the strength of the reaction. He makes one surprising statement to the effect that relapses after one dose of salvarsan are comparatively few.

Noguchi is still a most enthusiastic believer in the simplicity and practicability of his test. He maintains vigorously that the carrying out of the test does not require especial training. That this is so—that the Noguchi system materially reduces the difficulties of the serum-test—is far from evident, even from his own description of it. His idea, in this connection, that the

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